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Symbol
Name
ID

Blnk
B cell linker
MGI:96878

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgA level	Decreased circulating IgG level	Decreased circulating total IgM	Agammaglobulinemia	Neutropenia	Abnormal T cell morphology
Disease(s) Associated with BLNK
agammaglobulinemia 4

Mouse Phenotypes

abnormal B cell apoptosis

increased B cell apoptosis

decreased B cell proliferation

enlarged spleen

abnormal B cell differentiation

abnormal immature B cell morphology

decreased immature B cell number

decreased transitional stage B cell number

abnormal plasma cell differentiation

increased pro-B cell number

arrested B cell differentiation

decreased basophil cell number

increased eosinophil cell number

increased neutrophil cell number

decreased mature B cell number

absent B-1a cells

absent B-1b cells

decreased B-1a cell number

decreased follicular B cell number

decreased marginal zone B cell number

increased mature B cell number

decreased B cell number

decreased pre-B cell number

increased pre-B cell number

increased CD4-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased lymphocyte cell number

decreased large unstained cell number

decreased leukocyte cell number

abnormal mature B cell morphology

abnormal pre-B cell morphology

decreased spleen weight

small spleen

spleen hypoplasia

decreased splenocyte number

abnormal B cell activation

decreased IgG3 level

decreased IgG level

decreased IgM level

decreased immunoglobulin level

Availability

Mouse Genotype

Blnk^em1(IMPC)H/Blnk^em1(IMPC)H

Blnk^m1Btlr/Blnk^m1Btlr

Blnk^tm1Achn/Blnk^tm1Achn

Blnk^tm1Dkit/Blnk^tm1Dkit

Blnk^tm1Kplm/Blnk^tm1Kplm

Blnk^tm1Pjln/Blnk^tm1Pjln

Blnk^tm1Achn/Blnk⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23